これまでの主な研究成果
Waki T, Tanaka-Mizuno S, Takashima N, Takechi H, Hayakawa T, Miura K, Ueshima H, Kita Y, Dodge HH
Waist Circumference and Domain-Specific Cognitive Function among Non-demented Japanese Older Adults Stratified by Sex: Results from the Takashima Cognition Study.
Journal of Alzheimer's Disease. 2020;73(3):887-896. doi:10.3233/JAD-190395
Nakatochi M, Kanai M, Nakayama A, Hishida A, Kawamura Y, Ichihara S, Akiyama M, Ikezaki H, Furusyo N, Shimizu S, Yamamoto K, Hirata M, Okada R, Kawai S,
Kawaguchi M, Nishida Y, Shimanoe C, Ibusuki R, Takezaki T, Nakajima M, Takao M, Ozaki E, Matsui D, Nishiyama T, Suzuki S, Takashima N, Kita Y, Endoh K,
Kuriki K, Uemura H, Arisawa K, Oze I, Matsuo K, Nakamura Y, Mikami H, Tamura T, Nakashima H, Nakamura T, Kato N, Matsuda K, Murakami Y, Matsubara T, Naito M,
Kubo M, Kamatani Y, Shinomiya N, Yokota M, Wakai K, Okada Y, Matsuo H.
Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals.
Commun Biol. 2019;2:115. doi: 10.1038/s42003-019-0339-0.
Ohkuma T, Ninomiya T, Tomiyama H, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Aboyans V, Yamashina A;
collaborative group for the Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies to examine the significance of the Ankle-Brachial Index (J-BAVEL-ABI).
Ankle-brachial index measured by oscillometry is predictive for cardiovascular disease and premature death in the Japanese population: An individual participant data meta-analysis.
Atherosclerosis. 2018;275:141-148. doi: 10.1016/j.atherosclerosis.2018.05.048.
Tomiyama H, Ohkuma T, Ninomiya T, Mastumoto C, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Yamashina A;
collaborative group for J-BAVEL-IAD (Japan Brachial-Ankle Pulse Wave Velocity Individual Participant Data Meta-Analysis of Prospective Studies to Examine the Significance of Inter-Arm Blood Pressure Difference).
Simultaneously Measured Interarm Blood Pressure Difference and Stroke: An Individual Participants Data Meta-Analysis.
Hypertension. 2018;71:1030-1038. doi: 10.1161/HYPERTENSIONAHA.118.10923.
Ohkuma T, Tomiyama H, Ninomiya T, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Yamashina A;
Proposed Cutoff Value of Brachial-Ankle Pulse Wave Velocity for the Management of Hypertension.
Collaborative Group for Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies (J-BAVEL).
Circ J. 2017;81:1540-1542. doi: 10.1253/circj.CJ-17-0636.
Hachiya T, Kamatani Y, Takahashi A, Hata J, Furukawa R, Shiwa Y, Yamaji T, Hara M, Tanno K, Ohmomo H, Ono K, Takashima N, Matsuda K, Wakai K, Sawada N, Iwasaki M, Yamagishi K, Ago T, Ninomiya T, Fukushima A,
Hozawa A, Minegishi N, Satoh M, Endo R, Sasaki M, Sakata K, Kobayashi S, Ogasawara K, Nakamura M, Hitomi J, Kita Y, Tanaka K, Iso H, Kitazono T, Kubo M,
Tanaka H, Tsugane S, Kiyohara Y, Yamamoto M, Sobue K, Shimizu A.
Genetic Predisposition to Ischemic Stroke: A Polygenic Risk Score.
Stroke. 2017;48:253-258. doi: 10.1161/STROKEAHA.116.014506.
Takashima N, Turin TC, Matsui K, Rumana N, Nakamura Y, Kadota A, Saito Y, Sugihara H, Morita Y, Ichikawa M, Hirose K, Kawakani K, Hamajima N, Miura K, Ueshima H, Kita Y.
The relationship of brachial-ankle pulse wave velocity to future cardiovascular disease events in the general Japanese population: the Takashima Study.
J Hum Hypertens. 2014;28:323-7. doi: 10.1038/jhh.2013.103.
Turin TC, Kita Y, Rumana N, Takashima N, Kadota A, Matsui K, Sugihara H, Morita Y, Nakamura Y, Miura K, Ueshima H.
Brachial-ankle pulse wave velocity predicts all-cause mortality in the general population: findings from the Takashima study, Japan.
Hypertens Res. 2010;33:922-5. doi: 10.1038/hr.2010.103.
Tabara Y, Kohara K, Kita Y, Hirawa N, Katsuya T, Ohkubo T, Hiura Y, Tajima A, Morisaki T, Miyata T, Nakayama T, Takashima N, Nakura J, Kawamoto R, Takahashi N, Hata A, Soma M, Imai Y,
Kokubo Y, Okamura T, Tomoike H, Iwai N, Ogihara T, Inoue I, Tokunaga K, Johnson T, Caulfield M, Munroe P; Global Blood Pressure Genetics Consortium, Umemura S, Ueshima H, Miki T.
Common variants in the ATP2B1 gene are associated with susceptibility to hypertension: the Japanese Millennium Genome Project.
Hypertension. 2010;56:973-80. doi: 10.1161/HYPERTENSIONAHA.110.153429.
Dodge HH, Kita Y, Takechi H, Hayakawa T, Ganguli M, Ueshima H.
Healthy cognitive aging and leisure activities among the oldest old in Japan: Takashima study.
J Gerontol A Biol Sci Med Sci. 2008;63(11):1193-200